Coenzyme Q10 (CoQ10) Powder, HPLC 98.0%–101.0%

Coenzyme Q10 Powder (HPLC 98.0%–101.0%)

Product Type: Coenzyme Q10 raw material

Product Name: Coenzyme Q10, Q10, CoQ10, Ubidecarenone

CAS Number: 303-98-0

EINECS Number: 206-147-9

Molecular Formula: C59H90O4

Molecular Weight: 863.36

Appearance: Orange-yellow crystalline powder

Solubility: Practically insoluble in water; soluble in acetone; very slightly soluble in ethanol

Assay (HPLC, anhydrous basis): 98.0%–101.0%

Pharmacopeia Compliance: USP, EP

Description:

Coenzyme Q10 powder, also known as ubiquinone or CoQ10, is a high-purity quinone compound widely used as a functional raw material in lipid-based formulation systems. This Coenzyme Q10 is manufactured under controlled production conditions and complies with USP quality requirements, with an HPLC assay range of 98.0%–101.0% on an anhydrous basis, ensuring consistent composition, batch-to-batch stability, and formulation reliability for professional applications.

Structurally, Coenzyme Q10 is a naturally occurring lipid-associated quinone characterized by a long polyisoprenoid side chain, which gives the CoQ10 molecule strong affinity for oil phases. Due to this chemical structure, Coenzyme Q10 is practically insoluble in water and exhibits very limited water solubility, while remaining compatible with oils and selected organic solvents. This property makes Coenzyme Q10 particularly suitable for oil-based systems, softgel encapsulation, emulsions, and lipid premixes where uniform distribution in non-aqueous matrices is required. The material appears as an odorless orange-yellow crystalline powder with controlled physical characteristics suitable for downstream processing and formulation.

In biochemical research and formulation science, CoQ10 is widely recognized as a coenzyme involved in electron transfer processes within the mitochondrial electron transport chain. This fundamental biochemical role has established Coenzyme Q10 as a commonly used ingredient in formulations related to cellular energy pathways, redox-associated systems, and lipid-compatible delivery formats. As a lipid-associated quinone, Coenzyme Q10 maintains functional stability when properly handled, and protection from light, heat, oxygen, and moisture is recommended to preserve the quality of Coenzyme Q10 during storage, transportation, and formulation.
High-purity coenzyme Q10 powder (ubiquinone), lipid-soluble quinone suitable for oil-based formulations and softgel applications.

Quality Index:

Characteristics	Units	Specification
Assay(HPLC)		98.0-101.0%
Moisture	%	Max 0.2
Residue on Ignition	%	Max 0.1
Related Substance (HPLC)	%	Total impurity <1.0 Single impurity <0.3
Identification	-	color reaction-positive re-action;infrared identification sample chromatography complies to standard sample's
Residual Solvent	-	Up to specification
Heavy Metal	%	Max 0.002
Total Plate Count	cfu/g	Max 1000
Yeasts and Molds	cfu/g	Max 100
E. coli/1g	-	Absent

Function:

1. Mitochondrial Energy Pathway Support

Coenzyme Q10 functions as a lipid-soluble coenzyme within the mitochondrial inner membrane, where it participates in electron transfer processes associated with oxidative phosphorylation. As a fat-soluble CoQ10 raw material, it is structurally suited for research and formulation systems focused on cellular energy metabolism and ATP-related biochemical pathways.

2. Electron Transport Chain Participation

Fat-soluble Coenzyme Q10 plays a structural and functional role in electron transport between respiratory complexes, supporting studies and formulations related to redox balance and energy-related biochemical mechanisms. Its quinone structure enables reversible oxidation–reduction behavior in lipid environments.

3. Antioxidant-Related Activity in Lipid Systems

Due to its chemical structure, ubiquinone exhibits antioxidant-associated properties in oil-based matrices. Coenzyme Q10 powder is commonly used in formulations designed to support oxidative stability in lipid phases, making it suitable for applications requiring fat-soluble antioxidant functionality.

4. Cellular Metabolism Research Compatibility

As a naturally occurring compound present in eukaryotic cells, CoQ10 is widely applied as a reference ingredient in studies and formulations related to cellular metabolism, mitochondrial function, and energy-associated biochemical systems.

5. Formulation Stability and Lipid Affinity

The long polyisoprenoid side chain of fat-soluble Coenzyme Q10 provides strong affinity for oils and non-aqueous carriers, allowing stable dispersion and compatibility in lipid-based delivery systems without the need for water solubilization.
Coenzyme Q10 functions as a lipid-associated quinone supporting mitochondrial electron transfer, energy-related biochemical pathways, antioxidant activity in lipid systems, and compatibility with oil-based formulation research.

Coenzyme Q10 functions as a lipid-associated quinone supporting mitochondrial electron transfer, energy-related biochemical pathways, antioxidant activity in lipid systems, and compatibility with oil-based formulation research.

Application:

1. Dietary Supplement Formulations

Fat-soluble Coenzyme Q10 is widely used as a raw material in softgel capsules, oil suspensions, and lipid-filled dosage forms. Its solubility profile makes it suitable for formulations where CoQ10 is delivered in an oil phase to ensure homogeneous distribution and formulation consistency.

2. Functional Food and Nutritional Systems

Coenzyme Q10 powder can be incorporated into functional food premixes, lipid-based nutritional products, and specialized formulation systems requiring fat-soluble ubiquinone as a functional ingredient component.

3. Cosmetic and Personal Care Products

In cosmetic formulations, Coenzyme Q10 is applied in creams, serums, emulsions, and oil-based skincare systems where lipid compatibility is required. Its fat-soluble nature allows integration into oil phases commonly used in personal care product development.

4. Pharmaceutical and Research Applications

Coenzyme Q10 meeting USP standards is suitable for pharmaceutical raw material supply chains and laboratory research, including formulation development, analytical studies, and ingredient evaluation related to mitochondrial and energy-associated pathways.

5. Ingredient Premix and OEM Manufacturing

Fat-soluble CoQ10 is used by OEM and contract manufacturers as a standardized raw material for customized formulations, blends, and premixes where high purity, controlled quality parameters, and consistent performance are required.

Package:

Inside: vacuumed aseptic PE bags/aluminum tins,5kg per tin.

Outside: carton

Packages size can also be offered according to customer requirement.

Storage and Stability:

Sensitive to oxygen, heat, light and moisture.

The product should be contained in unopened original package, protected from light in a dry place at low temperature(<15c). Once it is opened, please use it up in short time.

The Shelf life is 24 months for the unopened product stored in recommended condition.

Coenzyme Q10 Powder — FAQ Section

1. What is Coenzyme Q10 powder?

Coenzyme Q10 powder, also known as ubiquinone or CoQ10, is a lipid-associated quinone compound widely used as a functional raw material in oil-based and lipid-compatible formulation systems.

2. Is Coenzyme Q10 powder water soluble?

Standard high-purity Coenzyme Q10 powder is practically insoluble in water due to its chemical structure and long polyisoprenoid side chain. It is primarily designed for oil-based systems.

Cold water soluble (CWS) Coenzyme Q10 is available as a formulated form with lower CoQ10 content, allowing dispersion in aqueous systems.

3. What CoQ10 contents are available for CWS Coenzyme Q10?

CWS Coenzyme Q10 is available in standardized contents of 10%, 20%, and 40%, providing flexible options for different water-dispersible formulation requirements.

4. What is the difference between high-purity CoQ10 and CWS CoQ10?

High-purity Coenzyme Q10 powder is intended for lipid-based delivery formats such as oils, softgels, and emulsions, while CWS CoQ10 is a formulated, lower-content version designed for aqueous systems.

5. Which formulations commonly use Coenzyme Q10 powder?

High-purity Coenzyme Q10 powder is widely used in softgels, oil suspensions, lipid premixes, and cosmetic emulsions, whereas CWS CoQ10 is more suitable for beverages, instant powders, granules, and other water-dispersible formulations.

6. Why is Coenzyme Q10 commonly used in softgel formulations?

Softgel systems provide an oil-based environment that allows Coenzyme Q10 to dissolve evenly and maintain stability during processing and storage.

7. Does the content level of CoQ10 affect formulation behavior?

Yes. Higher-purity Coenzyme Q10 is more suitable for lipid-based systems, while lower-content CWS CoQ10 is specifically designed to improve dispersibility in water-based formulations.

8. What does Coenzyme Q10 powder look like?

Coenzyme Q10 powder typically appears as an orange-yellow to yellow crystalline powder with controlled physical characteristics suitable for formulation processing.

9. How should Coenzyme Q10 powder be handled and stored?

Coenzyme Q10 powder should be protected from light, heat, oxygen, and moisture during storage and formulation to help maintain product stability and quality.

Looking for a reliable supplier of high-purity Coenzyme Q10 powder or CWS CoQ10 (10%, 20%, or 40%) for different formulation systems?

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